What's it like to take Sublocade?
- The injection may be uncomfortable. Some people describe a hot or burning feeling when the medication is injected under the skin. Using an ice pack on the area before and after the injection usually helps to make it less painful.
- Medical examination and laboratory tests, where appropriate
- After the injection, the medication forms a small bump under the skin. The bump can last from four weeks up to a few months, but it will gradually go away.
- After the injection, some people feel a little bit sleepy. Most people feel completely normal. Over the month, most people feel very level and don’t notice any withdrawal symptoms.
If you miss a dose, it can be given up to two weeks late.
Is Sublocade right for me?
- ...don't want to attend a pharmacy every day or every week.
- ...travel frequently.
- ...experience withdrawal symptoms or cravings on Suboxone.
- ...don't like the taste or feel of Suboxone.
Sublocade is not considered to be safe in pregnancy because of the gel added to the buprenorphine. People who could become pregnant should only use Sublocade if they're using an effective form of birth control, and should have a pregnancy test before each injection unless they have a long-term birth control method, like an IUD.
How are Sublocade and Suboxone different?
| Comparison | SUBLOCADE | SUBOXONE |
|---|---|---|
| How it's taken | Monthly injection | Daily pill taken under the tongue |
| Side effects | Can cause soreness and a bump where the needle goes in | Can cause nausea or dry mouth, may taste bad |
| Starting | Must be on a daily Suboxone dose of at least 8mg for at least a week | Must be in opioid withdrawal before starting (unless microdosing) |
| Dose | 300mg for two months, then 100mg | Daily doses range from 2mg to 24mg |
| Withdrawal | Mild symptoms may occur 4 weeks after injection | Symptoms often happen 24 hours after a dose |
| Missed doses | If an injection is missed, it can be given up to 2 weeks late without changing the dose | If more than a week is missed, the dose will need to be adjusted |
How it's taken
- Sublocade
- Monthly injection
- Suboxone
- Daily pill taken under the tongue
Side effects
- Sublocade
- Can cause soreness and a bump where the needle goes in
- Suboxone
- Can cause nausea or dry mouth, may taste bad
Starting
- Sublocade
- Must be on a daily Suboxone dose of at least 8mg for at least a week
- Suboxone
- Must be in opioid withdrawal before starting (unless microdosing)
Dose
- Sublocade
- 300mg for two months, then 100mg
- Suboxone
- Daily doses range from 2mg to 24mg
Withdrawal
- Sublocade
- Mild symptoms may occur 4 weeks after injection
- Suboxone
- Symptoms often happen 24 hours after a dose
Missed doses
- Sublocade
- If an injection is missed, it can be given up to 2 weeks late without changing the dose
- Suboxone
- If more than a week is missed, the dose will need to be adjusted
What if I take opioids while I'm on Sublocade?
- Because taking Sublocade will help control your cravings and withdrawal symptoms, you won't have to keep using your usual opioid to avoid being sick. You can still take it if you want to, but it becomes your choice.
- Sublocade makes you less likely to die of an overdose if you keep using opioids.
What else can I do to stay safer?
- Never use opioids alone; go to a safe consumption site, use with a friend, or contact the National Overdose Response Service
- Make sure you can recognize the signs of overdose: pinpoint pupils, falling asleep, slowed or stopped breathing, bluish skin around lips or under nails
- Always carry naloxone
- If you haven’t taken opioids for even a few days, take a much smaller dose than you are used to
- Get your drugs checked before using
- If you can’t get your drugs checked, start with a test dose
- Don’t mix opioids with other substances, especially alcohol or benzos
- If you inject or smoke drugs, use new supplies each and every time, including sterile cookers and filters, sterile water, mouthpieces, bowls, and screens. Supplies are available through your local harm reduction program
HOW DO I ACCESS THE PROGRAM?
Please visit Monday through Friday (8:00 a.m. – 5:00 p.m., EST) and identify yourself as a patient who is interested in our Sublocade program. Your family physician, psychiatrist, clinical psychologist, addiction counselor, other allied health professional, or employer may also call on your behalf for further information.
No appointment necessary! Walk-ins welcome.

WHY SHOULD YOU START A TREATMENT PROGRAM?
If any of the following benefits are desirable to you, or are part of your future goals, then you should give our program your attention and consideration:
- A drug-free lifestyle
- A stable personal, social, family and financial life
- No physical withdrawal symptoms
- Decreased or eliminated drug cravings
- Resolution of legal concerns
- Improved health and the prevention of drug related health problems (e.g., HIV, Hepatitis, Liver disease, etc.)
- A chance to obtain or complete an education
- A chance at stable employment
- Improved self-esteem, self-worth & independence
- Improved memory, concentration, attention & thinking
- Improved overall quality of life
- A chance to regain respect, trust and relationships with your spouse, children, family members, friends and associates
